01 - Preheat oven to 425°F. Line a large baking sheet with parchment paper and lightly coat with non-stick spray.
02 - Whisk together flour, milk, garlic powder, onion powder, smoked paprika, salt, and black pepper in a large bowl until smooth.
03 - Dip each cauliflower floret into the batter, letting excess drip off, then dredge evenly in panko breadcrumbs. Arrange in a single layer on the prepared baking sheet.
04 - Lightly spray coated florets with cooking spray. Bake for 20 minutes, flipping halfway, until golden and crisp.
05 - Combine hot sauce, melted butter, and honey in a small bowl; stir until well mixed.
06 - In a separate bowl, mix mayonnaise, sour cream, lemon juice, dill, chives, garlic powder, onion powder, salt, and pepper until smooth. Chill until serving.
07 - Transfer baked cauliflower to a large bowl, pour buffalo sauce over, and toss gently to coat evenly.
08 - Return coated florets to the baking sheet and bake for an additional 10 minutes to enhance crispiness.
09 - Serve hot with chilled ranch dip on the side.